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eribulin mesylate  (MedChemExpress)


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    MedChemExpress eribulin mesylate
    <t>Eribulin</t> treatment reduces KSHV-NOK and HPV-NOK cell proliferation, migration, and invasion. KSHV-NOK and HPV-NOK cells were seeded on plates and cultured in E media containing 5% FBS and EGF overnight. Cells were then cultured in E media with eribulin for the indicated times ( A, B ) or 8 days ( C through G ). ( A ) Representative brightfield images shown were taken with the 20× objective of a Leica DMi8 fluorescent microscope, scale bar, 100 μm. ( B ) Quantification of live and dead cells is depicted. The graph represents the average of triplicate wells, and error bars represent mean ± SD. P -values were analyzed using two-way analysis of variance (ANOVA) with Dunnett multiple comparisons. ( C ) EMT markers were detected after KSHV-NOK and HPV-NOK cells were treated with eribulin. ( D ) Migration assay of eribulin-treated-KSHV-NOK and HPV-NOK. Representative images of migrated cells shown were taken under the 10× objective of a Leica DMi8 fluorescent microscope, scale bar, 100 μm. ( E ) Quantification of migrated cells from ( D ) is depicted. ( F ) Invasion assay of eribulin-treated KSHV-NOK and HPV-NOK cells. Representative images of invaded cells shown were taken with the 10× objective of a Leica DMi8 fluorescent microscope, scale bar, 100 μm. ( G ) Quantification of invaded cells from ( F ) is depicted. Panels A, C, and D show representative images of three independent experiments, while panel F shows representative images of four independent experiments. Graph E represents the average of three independent experiments while panel G represents the average of four independent experiments, and error bars represent mean ± SEM. P -values were analyzed using two-way ANOVA with Sidak multiple comparisons for panels E and G.
    Eribulin Mesylate, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 93/100, based on 5 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/eribulin mesylate/product/MedChemExpress
    Average 93 stars, based on 5 article reviews
    eribulin mesylate - by Bioz Stars, 2026-02
    93/100 stars

    Images

    1) Product Images from "KSHV and HPV modulate epithelial-to-mesenchymal transition in oral epithelial cells"

    Article Title: KSHV and HPV modulate epithelial-to-mesenchymal transition in oral epithelial cells

    Journal: mBio

    doi: 10.1128/mbio.00484-25

    Eribulin treatment reduces KSHV-NOK and HPV-NOK cell proliferation, migration, and invasion. KSHV-NOK and HPV-NOK cells were seeded on plates and cultured in E media containing 5% FBS and EGF overnight. Cells were then cultured in E media with eribulin for the indicated times ( A, B ) or 8 days ( C through G ). ( A ) Representative brightfield images shown were taken with the 20× objective of a Leica DMi8 fluorescent microscope, scale bar, 100 μm. ( B ) Quantification of live and dead cells is depicted. The graph represents the average of triplicate wells, and error bars represent mean ± SD. P -values were analyzed using two-way analysis of variance (ANOVA) with Dunnett multiple comparisons. ( C ) EMT markers were detected after KSHV-NOK and HPV-NOK cells were treated with eribulin. ( D ) Migration assay of eribulin-treated-KSHV-NOK and HPV-NOK. Representative images of migrated cells shown were taken under the 10× objective of a Leica DMi8 fluorescent microscope, scale bar, 100 μm. ( E ) Quantification of migrated cells from ( D ) is depicted. ( F ) Invasion assay of eribulin-treated KSHV-NOK and HPV-NOK cells. Representative images of invaded cells shown were taken with the 10× objective of a Leica DMi8 fluorescent microscope, scale bar, 100 μm. ( G ) Quantification of invaded cells from ( F ) is depicted. Panels A, C, and D show representative images of three independent experiments, while panel F shows representative images of four independent experiments. Graph E represents the average of three independent experiments while panel G represents the average of four independent experiments, and error bars represent mean ± SEM. P -values were analyzed using two-way ANOVA with Sidak multiple comparisons for panels E and G.
    Figure Legend Snippet: Eribulin treatment reduces KSHV-NOK and HPV-NOK cell proliferation, migration, and invasion. KSHV-NOK and HPV-NOK cells were seeded on plates and cultured in E media containing 5% FBS and EGF overnight. Cells were then cultured in E media with eribulin for the indicated times ( A, B ) or 8 days ( C through G ). ( A ) Representative brightfield images shown were taken with the 20× objective of a Leica DMi8 fluorescent microscope, scale bar, 100 μm. ( B ) Quantification of live and dead cells is depicted. The graph represents the average of triplicate wells, and error bars represent mean ± SD. P -values were analyzed using two-way analysis of variance (ANOVA) with Dunnett multiple comparisons. ( C ) EMT markers were detected after KSHV-NOK and HPV-NOK cells were treated with eribulin. ( D ) Migration assay of eribulin-treated-KSHV-NOK and HPV-NOK. Representative images of migrated cells shown were taken under the 10× objective of a Leica DMi8 fluorescent microscope, scale bar, 100 μm. ( E ) Quantification of migrated cells from ( D ) is depicted. ( F ) Invasion assay of eribulin-treated KSHV-NOK and HPV-NOK cells. Representative images of invaded cells shown were taken with the 10× objective of a Leica DMi8 fluorescent microscope, scale bar, 100 μm. ( G ) Quantification of invaded cells from ( F ) is depicted. Panels A, C, and D show representative images of three independent experiments, while panel F shows representative images of four independent experiments. Graph E represents the average of three independent experiments while panel G represents the average of four independent experiments, and error bars represent mean ± SEM. P -values were analyzed using two-way ANOVA with Sidak multiple comparisons for panels E and G.

    Techniques Used: Migration, Cell Culture, Microscopy, Invasion Assay



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    <t>Eribulin</t> treatment reduces KSHV-NOK and HPV-NOK cell proliferation, migration, and invasion. KSHV-NOK and HPV-NOK cells were seeded on plates and cultured in E media containing 5% FBS and EGF overnight. Cells were then cultured in E media with eribulin for the indicated times ( A, B ) or 8 days ( C through G ). ( A ) Representative brightfield images shown were taken with the 20× objective of a Leica DMi8 fluorescent microscope, scale bar, 100 μm. ( B ) Quantification of live and dead cells is depicted. The graph represents the average of triplicate wells, and error bars represent mean ± SD. P -values were analyzed using two-way analysis of variance (ANOVA) with Dunnett multiple comparisons. ( C ) EMT markers were detected after KSHV-NOK and HPV-NOK cells were treated with eribulin. ( D ) Migration assay of eribulin-treated-KSHV-NOK and HPV-NOK. Representative images of migrated cells shown were taken under the 10× objective of a Leica DMi8 fluorescent microscope, scale bar, 100 μm. ( E ) Quantification of migrated cells from ( D ) is depicted. ( F ) Invasion assay of eribulin-treated KSHV-NOK and HPV-NOK cells. Representative images of invaded cells shown were taken with the 10× objective of a Leica DMi8 fluorescent microscope, scale bar, 100 μm. ( G ) Quantification of invaded cells from ( F ) is depicted. Panels A, C, and D show representative images of three independent experiments, while panel F shows representative images of four independent experiments. Graph E represents the average of three independent experiments while panel G represents the average of four independent experiments, and error bars represent mean ± SEM. P -values were analyzed using two-way ANOVA with Sidak multiple comparisons for panels E and G.
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    Image Search Results


    Eribulin treatment reduces KSHV-NOK and HPV-NOK cell proliferation, migration, and invasion. KSHV-NOK and HPV-NOK cells were seeded on plates and cultured in E media containing 5% FBS and EGF overnight. Cells were then cultured in E media with eribulin for the indicated times ( A, B ) or 8 days ( C through G ). ( A ) Representative brightfield images shown were taken with the 20× objective of a Leica DMi8 fluorescent microscope, scale bar, 100 μm. ( B ) Quantification of live and dead cells is depicted. The graph represents the average of triplicate wells, and error bars represent mean ± SD. P -values were analyzed using two-way analysis of variance (ANOVA) with Dunnett multiple comparisons. ( C ) EMT markers were detected after KSHV-NOK and HPV-NOK cells were treated with eribulin. ( D ) Migration assay of eribulin-treated-KSHV-NOK and HPV-NOK. Representative images of migrated cells shown were taken under the 10× objective of a Leica DMi8 fluorescent microscope, scale bar, 100 μm. ( E ) Quantification of migrated cells from ( D ) is depicted. ( F ) Invasion assay of eribulin-treated KSHV-NOK and HPV-NOK cells. Representative images of invaded cells shown were taken with the 10× objective of a Leica DMi8 fluorescent microscope, scale bar, 100 μm. ( G ) Quantification of invaded cells from ( F ) is depicted. Panels A, C, and D show representative images of three independent experiments, while panel F shows representative images of four independent experiments. Graph E represents the average of three independent experiments while panel G represents the average of four independent experiments, and error bars represent mean ± SEM. P -values were analyzed using two-way ANOVA with Sidak multiple comparisons for panels E and G.

    Journal: mBio

    Article Title: KSHV and HPV modulate epithelial-to-mesenchymal transition in oral epithelial cells

    doi: 10.1128/mbio.00484-25

    Figure Lengend Snippet: Eribulin treatment reduces KSHV-NOK and HPV-NOK cell proliferation, migration, and invasion. KSHV-NOK and HPV-NOK cells were seeded on plates and cultured in E media containing 5% FBS and EGF overnight. Cells were then cultured in E media with eribulin for the indicated times ( A, B ) or 8 days ( C through G ). ( A ) Representative brightfield images shown were taken with the 20× objective of a Leica DMi8 fluorescent microscope, scale bar, 100 μm. ( B ) Quantification of live and dead cells is depicted. The graph represents the average of triplicate wells, and error bars represent mean ± SD. P -values were analyzed using two-way analysis of variance (ANOVA) with Dunnett multiple comparisons. ( C ) EMT markers were detected after KSHV-NOK and HPV-NOK cells were treated with eribulin. ( D ) Migration assay of eribulin-treated-KSHV-NOK and HPV-NOK. Representative images of migrated cells shown were taken under the 10× objective of a Leica DMi8 fluorescent microscope, scale bar, 100 μm. ( E ) Quantification of migrated cells from ( D ) is depicted. ( F ) Invasion assay of eribulin-treated KSHV-NOK and HPV-NOK cells. Representative images of invaded cells shown were taken with the 10× objective of a Leica DMi8 fluorescent microscope, scale bar, 100 μm. ( G ) Quantification of invaded cells from ( F ) is depicted. Panels A, C, and D show representative images of three independent experiments, while panel F shows representative images of four independent experiments. Graph E represents the average of three independent experiments while panel G represents the average of four independent experiments, and error bars represent mean ± SEM. P -values were analyzed using two-way ANOVA with Sidak multiple comparisons for panels E and G.

    Article Snippet: Eribulin mesylate was purchased from Med Chem Express (catalog number is HY-13442A).

    Techniques: Migration, Cell Culture, Microscopy, Invasion Assay